I have many dual homed asterisk boxes that work fine. Kernel IP routing table Destination Gateway Genmask Flags MSS Window irtt Iface 172.18.192.0 0.0.0.0 255.255.240.0 U 40 0 0 eth0 10.10.0.0 0.0.0.0 255.255.0.0 U 40 0 0 eth1 0.0.0.0 172.18.207.254 0.0.0.0 UG 40 0 0 eth0 Asterisk binds to: udp 0 0 0.0.0.0:5060 0.0.0.0:*